Although influenza is a major public health concern, little is known about the use of spray live attenuated influenza vaccine (LAIV) among adults. For this reason, we conducted a systematic review and meta-analysis to investigate the efficacy and safety

Question Does vaccine effectiveness differ between live attenuated influenza vaccine and inactivated influenza vaccine in children and adolescents? Findings This test-negative study compared health administrative data and laboratory test results on respiratory

Together with inactivated influenza vaccines (IIV), live attenuated influenza vaccines (LAIV) are an important tool to prevent influenza A virus (IAV) illnesses in patients. LAIVs present the advantages to have a needle-free administration and to trigger